Pharmacological kev txiav txim ntawm cinnamon extract

Cinnamon extract yog ib qho muab tau los ntawm cov tawv ntoo lossis cov tawv nqaij qhuav ntawm Cinnamon tsob ntoo cinnamon, feem ntau yog xim daj lossis amber kua, tsw qab tshwj xeeb, qab qab. Me ntsis soluble hauv dej, soluble hauv ethanol thiab ether, insoluble hauv roj av ether. Nws muaj kev tiv thaiv oxidation, tiv thaiv ntshav qab zib, tiv thaiv qog, tiv thaiv kab mob thiab lwm yam cuam tshuam.

Pharmacological kev txiav txim ntawm cinnamon extract

1. Cov nyhuv Antioxidant: Cov dej extract ntawm cov cinnamon muaj qee yam los tiv thaiv oxidation, thiab nws tau pom tias inhibit lipid peroxidation hauv vitro. Cov nyhuv los tiv thaiv oxidation ntawm cinnamon tau kawm los ntawm DPPH txujci, thiab cov dej num antioxidant tau qhia los ntawm tus nqi inhibition. Thaum lub concentration ntawm cinnamon yog 5 mg / ml, qhov thev tsis haum yog 94,2%. Thaum cov tshuaj extract tau diluted 5 zaug, uas yog, cov tshuaj lom yog 1 mg / ml, qhov tshuaj tiv thaiv yog 92.9%, qhia tias cinnamon muaj cov tshuaj tiv thaiv antioxidant muaj zog.

2. Cov nyhuv tshuaj tiv thaiv: Cinnamon extract tuaj yeem tiv thaiv qhov kev hais tawm ntawm cyclooxygenase-2 thiab carbon monoxide synthase hauv RAW2647 hlwb kuaj kab mob hauv vitro, thiab muaj cov tshuaj los tiv thaiv. Cinnamon muaj qee yam kev cuam tshuam ntawm kev hloov kho mob thiab mob huam. Piv txwv, nws muaj qhov cuam tshuam rau carrageenan-ntxias cov pob taws o thiab nce capillary permeability hauv cov nas, thiab muaj cov kev tiv thaiv ntawm kev mob caj dab, thiaj li tiv thaiv cov tsos mob thib ob ntawm tag nrho lub cev.

3. Qhov cuam tshuam ntawm lub plab zom mov: Cinnamon dej extract muaj qhov cuam tshuam pom tseeb ntawm lub plab zom mov thiab serotonin-vim yog mob viav vias hauv cov nqaij txias lossis dej-ua kom muaj kev ntxhov siab, tiv thaiv kom tsis txhob mob plab cov kua txiv thiab ua rau muaj cov leeg ntshav cov ntshav tawm hauv cov nas. Txaus tus nqi.

4. Qhov cuam tshuam rau cov ntshav ntawm cov ntshav: Hauv kev kuaj hauv vitro tau pom tias cinnamon methanol extract, cinnamaldehyde tuaj yeem tiv thaiv platelet kev sib xyaw thiab antithrombin kev txiav txim siab, thiab cinnamic acid kuj muaj cov nyhuv antithrombin. Hauv kev sim vivo qhia pom tias methanol extract ntawm cov cinnamon inhibited sim ua kom pom kev mob thrombosis los ntawm endotoxin hauv nas. Tsis tas li ntawd, cov tshuaj cinnamyl cawv kuj tseem tuaj yeem ua rau lub siab tsis haum, mob ntshav, thiab lwm yam los ntawm endotoxin.

5. Kev ua haujlwm ntawm lub cev tiv thaiv kab mob: Cinnamon extract tuaj yeem txo qhov tsis muaj kabmob ua haujlwm thiab lub zog tiv thaiv kab mob, thiab txo qhov hnyav ntawm hnoos qeev nyob rau hauv cov menyuam hluas, tab sis tsis muaj teebmeem rau thymus qhov hnyav, thiab tsis muaj qhov cuam tshuam rau qhov tsis haum rau lub cev nas.

6. Cov nyhuv los tiv thaiv ntshav qab zib: Cinnamon extract tuaj yeem tswj lub cev zoo nyob hauv qab thiab txhim kho lub cev rhiab rau insulin. Cov phenolic oligomer hauv CE muaj cov txiaj ntsig ntawm kev txo cov ntshav qab zib. Cov koob tshuaj sib txawv ntawm CE14d tau muab, uas tuaj yeem txo cov qauv tsiaj. Cov ntshav qab zib cov ntshav qab zib, cov tshuaj insulin ntau ntxiv, txo qis tom qab hnub kawg.

7. Cov nyhuv los tiv thaiv qog: Cov ntsiab lus ntawm tag nrho cov phenolic tshuaj (TPC), quercetin thiab kaempferol hauv cinnamon yog siab dua lwm cov nroj tsuag, thiab nws yog ib qho antioxidant nquag cog, ob qho tib si hauv vivo thiab hauv vitro. Nws tau pom tias muaj cov nyhuv los tiv thaiv qog. Nws cov nyhuv los tiv thaiv qog cuam tshuam txog nws qhov kev tshem tawm ntawm superoxide radicals thiab inhibition ntawm oxidation cov tshuaj tiv thaiv.

8. Antimicrobial kev txiav txim siab: Cov roj cinnamon tuaj yeem thaiv txoj kev loj hlob ntawm txoj hnyuv es Escherichia coli. Qhov sib ntxiv ntawm cov cinnamon mus rau Volga muaj qhov cuam tshuam pom tseeb tshaj plaws rau Helicobacter pylori, uas cuam tshuam txog cov dej ua antioxidant ntawm cov nroj tsuag.

Lwm yam kev cuam tshuam: Cinnamon dej extract thiab cov roj ua tsis huv muaj qhov cuam tshuam tseem ceeb ntawm cov roj ntsha triglyceride nrog dej khov dej ntxhov siab hauv nas. Cinnamon ether extract tuaj yeem ncua ntev lub sijhawm muaj sia nyob ntawm sodium nitrite (NaNO2) lom nas. Cov kev sim tau paub tseeb tias cov roj cinnamon muaj cov tshuaj kho tau tus mob coxsackie tus mob myocarditis hauv cov nas. Lub tshuab yuav cuam tshuam nrog dilating cov hlab ntsha, txhim kho microcirculation, kev tiv thaiv ischemia thiab hypoxia, nce kev noj haus ntshav ntim ntawm ischemic myocardium, yog li txhim kho myocardial metabolism thiab txo Oxygen dawb radical puas tsuaj rau myocardial hlwb thiab pab txhawb kev nqus ntawm o, yog li txo necrosis ntawm subacute myocardium thiab calcification. Tshuaj Kho Mob