Txoj Haujlwm ntawm Oleanolic acid

Oleanolic acid yog pentacyclic triterpenoid muab los ntawm cov txiv hmab txiv ntoo ntawm genus Asteraceae, Syzygium sylvestris, lossis Ligustrum lucidum, uas yog tam sim no nyob hauv lub cev dawb thiab glycoside. Cov nroj tsuag tau dhau los ua cov chaw siv tshuaj kho mob hepatoprotective, uas muaj qhov pom tseeb tiv thaiv kev mob siab thiab mob siab ntev los ntawm kev mob siab rau cov pa roj carbon tetrachloride, uas tuaj yeem nce siab ntxiv ALT thiab AST, o, mob necrosis thiab mob o. Txo cov lus teb, tiv thaiv fibrosis, txhawb kev tsim dua tshiab ntawm hepatocytes, thiab ua kom nrawm rov qab ntawm cov nqaij mos necrotic

Cov haujlwm ntawm oleanolic acid

1. Oleanolic acid muaj anti-inflammatory, sedative, cardiotonic, diuretic, hypolipidemic, hypoglycemic thiab daim siab tiv thaiv kab mob siab, txhim kho kev tiv thaiv kab mob thiab inhibit kev loj hlob ntawm S180 qog, yog kev txhim kho cov tshuaj muaj txiaj ntsig zoo rau kev kho kab mob siab thiab ntshav qab zib txos.

2. Nws muaj cov kev tiv thaiv ntawm kev puas tsuaj chromosomal thiab muaj kev tiv thaiv ntawm kev sim tshuaj atherosclerosis. Clinically siv rau kev kho mob los ntawm kev muaj kab mob siab daj ntseg mob siab, mob voos voos ntev, muaj kev txo qis tseem ceeb hauv alanine aminotransferase thiab cov tawv nqaij daj.

3. Nws muaj qhov ua haujlwm ntawm inhibiting daim siab fibrosis. Hauv nas nrog daim siab fibrosis kho nrog oleanolic acid, daim siab mob fibrosis hnyav thiab txo qis, thiab cov ntsiab lus ntawm hepatic collagen tsawg dua, qhia tias nws muaj cov txiaj ntsig ntawm kev tiv thaiv thiab kho daim siab ua haujlwm.

4. Nws tuaj yeem txo tus mob cirrhosis rat lub hlwb homogenate tyrosine qib: vim qhov txo qis tseem ceeb ntawm lub hlwb homogenate tyrosine qib, tuaj yeem cuam tshuam kev tsim pseudo-neurotransmitters, nws yog qhov zoo rau kev tiv thaiv thiab kho mob hepatic encephalopathy.

5. Nws cov tshuaj ntsiav yog cov tshuaj tsis yog kws kho mob rau tshuaj kho mob rau daim siab, siv rau kev kho mob rau qhov kho tus mob siab thiab mob ntev. Nws muaj qee qhov kev tiv thaiv ntawm daim siab ua rau mob siab, uas tuaj yeem txo qis kom muaj siab alanine aminotransferase, txhawb kev ua haujlwm ntawm daim siab ua haujlwm thiab ua kom kho sai sai ntawm cov nqaij mos necrotic.